The battle continues between proponents of antiarrhythmic drugs and catheter ablation as first-line treatment for paroxysmal atrial fibrillation (PAF). At present, it would appear...

Dronedarone (Multaq) is a benzofuran derivative similar to amiodarone but without the iodine moiety, which is believed to be responsible for the toxic effects of amiodarone, notably...

Most guidelines for the management of atrial fibrillation (AF) specify that patients should not be considered for a catheter ablation unless treatment with at least one antiarrhythmic...

A new study supports the contention that the antiarrhythmic drug dronedarone (Multaq) is largely ineffective and associated with a high incidence of adverse events. Dronedarone is a...

In July 2009 the US Food and Drug Administration approved the antiarrhythmic drug dronedarone (Multaq) for the treatment of atrial fibrillation (AF) in patients without severe...

It is estimated that 3% of Japanese people over the age of 70 years suffer from atrial fibrillation (AF) and this percentage is expected to increase to 4.5% over the next 20 years...

Dronedarone (Multaq) was introduced in 2009 as a safe and effective alternative to amiodarone which, although highly effective, has a substantial number of serious adverse...

It is generally assumed that candidates for catheter ablation of atrial fibrillation (AF) have failed therapy with at least one antiarrhythmic drug (AAD). However, recently published...

Early recurrence of atrial arrhythmias (atrial fibrillation, flutter or tachycardia) is common following a pulmonary vein isolation (PVI) procedure, but does not necessarily indicate...

Flecainide (Tambocor) is a class 1C antiarrhythmic drug that blocks the inflow of sodium into heart cells thereby slowing conduction through the heart. It increases the atrial...

Pharmaceutical drug therapy for atrial fibrillation is designed to either re-establish and maintain normal sinus rhythm (NSR) through the use of antiarrhythmic drugs...

Flecainide and propafenone are both effective in terminating AF episodes when used on demand at the onset of an episode. Studies have shown that these drugs effectively...

The on-demand or "pill-in-the-pocket" approach is now used by many paroxysmal afibbers to quickly and effectively terminate afib episodes and return to normal sinus...

Having been in permanent atrial fibrillation for an extended period is associated with a poorer outcome of catheter ablation. Japanese cardiologists/electrophysiologists now report...

Antiarrhythmic drug therapy (ADT) is usually the first approach to dealing with atrial fibrillation. However, the long-term efficacy of antiarrhythmics is not great with 60 to 80% of patients...

There is continuing controversy as to which is the safest and most effective way of preventing afib occurrence – antiarrhythmics (AADs) or catheter ablation. Professor Haissaguerre...

Amiodarone (Cordarone) is the most effective antiarrhythmic drug on the market today, although a recent trial found that its efficacy in keeping atrial fibrillation patients afib-free...

Early recurrence of atrial arrhythmias (atrial fibrillation, flutter or tachycardia) is common following a pulmonary vein isolation (PVI) procedure, but does not necessarily indicate failure...

It is now generally accepted that there is a connection between atrial fibrillation (AF) and the renin-angiotensin-aldosterone system (RAAS). Aldosterone causes inflammation...

The debate over whether catheter ablation or ongoing treatment with antiarrhythmic drugs (AADs) should be first-line treatment for symptomatic atrial fibrillation...

Amiodarone (Cordarone) is the most effective antiarrhythmic drug on the market today, although a recent trial found that its efficacy in keeping atrial fibrillation patients afib-free...

A team of Danish researchers report the results of a very large study aimed at determining the safety of antiarrhythmic drugs in a group of atrial fibrillation...

Amiodarone (Cordarone) is supposedly the most effective antiarrhythmic drug on the market today, although a recent trial found that its efficacy in keeping atrial...

Although the success of antiarrhythmic drugs in the treatment of atrial fibrillation (AF) leaves a lot to be desired, it is generally accepted that therapy with 2 or more antiarrhythmics...

Well over a thousand cases of rhabdomyolysis (an often fatal muscle disease) caused by the ingestion of statin drugs (atorvastatin [Lipitor], simvastatin...

There is increasing evidence that the renin-angiotensin-aldosterone system (RAAS) is involved in atrial fibrillation. (NOTE: This has been discussed in the Conference Room...

There is still widespread denial among North American cardiologists as to the existence of vagally-mediated AF (atrial fibrillation) and a pronounced tendency to treat...

Current guidelines for the management of atrial fibrillation (AF) recommend first-line treatment with antiarrhythmics. However, the efficacy of antiarrhythmics such as...